ASTar kits

An ASTar kit contains two disposables, a sample preparation cartridge and an AST disc.

Cartridge

The cartridge contains all reagents and disposable articles needed for sample preparation, concentration determination, dilution and growth medium adaptation.


The reagents for this are pre-deposited in the cartridge in the form of a combination of frozen or freeze-dried and room-temperature liquids. It also contains components for inte
rnal liquid transport and zones that are intended for temperature regulating the sample during the analysis.

The cartridge contains a function that filters millimetre-sized resin composites present in many types of blood culture bottles and otherwise risk interfering with the analysis. Finally, it also has barcodes for identifying and linking the cartridge and patient sample.

The cartridge is stored at room temperature.

AST disc

The AST disc is used for AST and concentration determination.

It contains culturing chambers with prefilled antimicrobials in various concentrations used for AST, chambers without antimicrobials used as controls, and chambers used to determine the concentration in the added sample. It also contains channels for quick and effective distribution of samples to the culturing chambers and structures that allow air supply to the chambers without the supply affecting the imaging analysis.

The number of culturing chambers totals more than 330, furthermore, the format and placement of the chambers is adapted for quick reading, a prerequisite for rapid analysis of the large number of chambers. The AST disc also contains a unique barcode for identification and linking to each respective sample preparation cartridge and patient.  

The disc is stored at room temperature.

Cartridge

The cartridge contains all reagents and disposable articles needed for sample preparation, concentration determination, dilution and growth medium adaptation.


The reagents for this are pre-deposited in the cartridge in the form of a combination of frozen or freeze-dried and room-temperature liquids. It also contains components for inte
rnal liquid transport and zones that are intended for temperature regulating the sample during the analysis.

The cartridge contains a function that filters millimetre-sized resin composites present in many types of blood culture bottles and otherwise risk interfering with the analysis. Finally, it also has barcodes for identifying and linking the cartridge and patient sample.

The cartridge is stored at room temperature.

AST disc

The AST disc is used for AST and concentration determination.

It contains culturing chambers with prefilled antimicrobials in various concentrations used for AST, chambers without antimicrobials used as controls, and chambers used to determine the concentration in the added sample. It also contains channels for quick and effective distribution of samples to the culturing chambers and structures that allow air supply to the chambers without the supply affecting the imaging analysis.

The number of culturing chambers totals more than 330, furthermore, the format and placement of the chambers is adapted for quick reading, a prerequisite for rapid analysis of the large number of chambers. The AST disc also contains a unique barcode for identification and linking to each respective sample preparation cartridge and patient.  

The disc is stored at room temperature.

ASTar BC G- panel

Preliminary panel for AST analysis of gram-negative bacteria (including fastidious pathogens) from positive blood cultures. 

Antimicrobial classAntimicrobial agentRange (mg/L) Non-FastidiousRange (mg/L) Fastidious# Dilutions
AminoglycosideAmikacin0.5-1289
AminoglycosideGentamicin0.25-328
AminoglycosideTobramycin 0.125-329
CarbapenemErtapenem0.015-49
CarbapenemImipenem0.03-1610
CarbapenemMeropenem0.125-6410
CarbapenemMeropenem-vaboractam0.06-3210
CephalosporinCefazolin0.25-167
CephalosporinCefepime0.25-649
CephalosporinCefotaxime0.015-12814
CephalosporinCefoxitin 1-647
CephalosporinCeftazidime0.25-649
CephalosporinCeftazidime-avibactam0.25-328
CephalosporinCeftolozane-tazobactam 0.125-329
CephalosporinCeftriaxone0.015-12814
CephalosporinCefuroxime 1-647
FluoroquinoloneCiprofloxacin0.015-810
FluoroquinoloneLevofloxacin 0.125-168
MiscellaneousTrimethoprim-sulfamethoxazole 0.06-169
MonobactamAztreonam0.25-649
PenicillinAmoxicillin-clavulanic acid1-326
PenicillinAmpicillin1-647
PenicillinAmpicillin-sulbactam EU0.5-1289
PenicillinAmpicillin-sulbactam US1-647
PenicillinPiperacillin-tazobactam0.5-25610
PolymyxinColistin0.25-86
TetracyclineTigecycline0.015-1611
CarbapenemMeropenem
0.03-89
CephalosporinCefotaxime0.015-28
CephalosporinCeftriaxone0.015-28
FluoroquinoloneLevofloxacin 0.015-28
PenicillinAmoxicillin-clavulanic acid0.5-327
PenicillinAmpicillin0.25-86

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Flexible solution enables future panel extensions

ASTar system can be extended to other types of clinical samples. The modular design of the sample preparation cartridge, in combination with the AST disc, allows for future adaptation to other sample types such as isolates, urine, respiratory and sterile aspirates.

  • Blood culture

    Blood culture

  • Isolates

    Isolates

  • Urine

    Urine

  • Respiratory

    Respiratory

Designed to simplify

ASTar posters and publications

Designed to simplify

ASTar posters and publications