Rapid AST directly from positive blood cultures
Isolates (P. aeruginosa, E. coli, K. pneumoniae, S. aureus and E. faecalis) were spiked in blood culture flasks with blood from healthy individuals and incubated until signaled positive.
Of the 476 bacteria-antimicrobial agent combinations tested, phenotypic AST results obtained within 6 hours showed 96% essential agreement and 95% categorical agreement compared to reference broth microdilution.
The AST technology has been extensively tested on clinically relevant pathogens in correct sample matrix;
- Over 224 different strains including several challenge strains
-25 different species
-Gram positive and gram negative bacteria
- 30 different antibiotics
- In total over 3000 bug-drug combinations to date – steadily increasing